Fast genome-wide functional annotation through orthology assignment by
eggNOG-mapper. Jaime Huerta-Cepas, Kristoffer Forslund, Luis Pedro Coelho, Damian Szklarczyk,
Lars
Juhl Jensen,
Christian von Mering & Peer Bork. Mol Biol Evol
(2017)
doi: 10.1093/molbev/msx148.
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated
orthology resource based on 5090 organisms and 2502 viruses. Jaime Huerta-Cepas, Damian Szklarczyk, Davide Heller, Ana Hernández-Plaza, Sofia
K Forslund, Helen Cook, Daniel R Mende, Ivica Letunic, Thomas Rattei, Lars
J Jensen, Christian von Mering, Peer Bork Nucleic Acids Res. 2019 Jan 8;
47(Database issue): D309–D314. doi: 10.1093/nar/gky1085
Method Overview
eggNOG-mapper v2 is a tool for functional annotation of large sets
of
sequences
based on
fast orthology assignments using precomputed eggNOG v5.0 clusters and phylogenies. The
method is illustrated in the following
figure: